Under the Hybrid Organic-Inorganic Nanocomposites activity, CdSe nanocrystals (6-10 nm) prepared by chemical route using TOP/ TOPO capping were dispersed in conducting PPV (p-phenylenevinylene) and P3HT (3-hexylthiophene) polymer matrices using a binary solvent mixture (pyridine-chloroform) respectively and tailored by altering the composition and concentration of NC’s in CP. Stern-Volmer plots indicate heterogeneous quenching of PL emission for smaller CdSe quantum dots ensuring efficient charge transfer process across polymer-CdSe interface. This heterogeneous quenching could be as a result of insufficient coverage of polymers on the surface of CdSe nanocrystallites due to phase segregation in PPV-CdSe nanocomposites. The superior stability of the surface bonds of P3HT-CdSe nanocomposites as compared to the corresponding PPV-CdSe nanocomposites can be elucidated from absence of PL decay. The smallest size of CdSe nanocrystallites in conjunction with the superior surface morphology of P3HT polymers could be the key for the realization of effective charge separation and transport in hybrid solar cells.